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Article

Role of SCFAs in gut microbiome and glycolysis for colorectal cancer therapy

19 Mar 2019

Abstract excerpt

Increased risk of colorectal cancer (CRC) is associated with altered intestinal microbiota as well as short-chain fatty acids (SCFAs) reduction of output The energy source of colon cells relies mainly on three SCFAs, namely butyrate (BT), propionate, and acetate, while CRC transformed cells rely mainly on aerobic glycolysis to provide energy. This review summarizes recent research results for dysregulated glucose...

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PMID: 30888065
DOI: 10.1002/jcp.28436

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