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Article

Next generation sequencing for detection of EGFR alterations in NSCLC: is more better?

Journal of clinical pathology - 1 Mar 2022

Batra Ullas, Nathany Shrinidhi, Sharma Mansi, Jain Parveen, Mehta Anurag

Abstract excerpt

AIMS: The emergence of sophisticated next generation sequencing (NGS) based technologies in routine molecular diagnostics has paved the way for robust and accurate detection of variants which may otherwise be missed on single gene testing. This study aims at highlighting the same premise in EGFR mutated non-small cell lung carcinoma (NSCLC). METHODS: 1350 cases of NSCLC were screened, of which 490 EGFR mutated...

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Identifiers

PMID: 33372105
DOI: 10.1136/jclinpath-2020-207212

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