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Article

Rapid and Highly Sensitive Detection of Therapeutically Relevant Oncogenic Driver Mutations in EBUS-TBNA Specimens From Patients With Lung Adenocarcinoma.

Clinical lung cancer - 1 Nov 2018

Oezkan Filiz, Herold Thomas, Darwiche Kaid, Eberhardt Wilfried E E, Worm Karl, Christoph Daniel C, Wiesweg Marcel, Freitag Lutz, Schmid Kurt-Werner, Theegarten Dirk, Hager Thomas, Koenig Michael J, He Kai, Taube Christian, Schuler Martin, Breitenbuecher Frank

Abstract excerpt

BACKGROUND: First-line afatinib treatment prolongs overall survival in patients with metastatic non-small-cell lung cancer (NSCLC) harboring exon 19 deletion of epidermal growth factor receptor (EGFRdelEx19) mutations. In contrast, Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) mutations are negative predictors for benefit from EGFR-targeting agents. Endobronchial ultrasound-guided transbronchial needle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30206042
DOI: 10.1016/j.cllc.2018.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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