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Article

Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles.

Genetic epidemiology - 1 Feb 2023

Spanbauer Charles, Pan Wei

Abstract excerpt

Using high-dimensional genetic variants such as single nucleotide polymorphisms (SNP) to predict complex diseases and traits has important applications in basic research and other clinical settings. For example, predicting gene expression is a necessary first step to identify (putative) causal genes in transcriptome-wide association studies. Due to weak signals, high-dimensionality, and linkage disequilibrium...

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PMID: 36349692
DOI: 10.1002/gepi.22505
PMCID: PMC9892284

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