Article

A flexible empirical Bayes approach to multivariate multiple regression, and its improved accuracy in predicting multi-tissue gene expression from genotypes

2022-11-23

Abstract excerpt

Predicting phenotypes from genotypes is a fundamental task in quantitative genetics. With technological advances, it is now possible to measure multiple phenotypes in large samples. Multiple phenotypes can share their genetic component; therefore, modeling these phenotypes jointly may improve prediction accuracy by leveraging effects that are shared across phenotypes . However, effects can be shared across phenot...

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Literature Corpus work: 48e25923-f7ef-50cc-a8f3-953abedf9425
DOI: 10.1101/2022.11.22.517471

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