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Article

KLF13 Loss-of-Function Mutations Underlying Familial Dilated Cardiomyopathy.

Journal of the American Heart Association - 15 Nov 2022

Guo Yu-Han, Wang Jun, Guo Xiao-Juan, Gao Ri-Feng, Yang Chen-Xi, Li Li, Sun Yu-Min, Qiu Xing-Biao, Xu Ying-Jia, Yang Yi-Qing

Abstract excerpt

Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a leading cause of heart failure and cardiac death. Accumulating evidence underscores the critical role of genetic defects in the pathogenesis of DCM, and >250 genes have been implicated in DCM to date. However, DCM is of substantial genetic...

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Identifiers

PMID: 36346048
DOI: 10.1161/JAHA.122.027578
PMCID: PMC9750085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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