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Article

The Impact of Highly Effective Modulator Therapy on Cystic Fibrosis Microbiology and Inflammation.

Clinics in chest medicine - 1 Dec 2022

Caverly Lindsay J, Riquelme Sebastián A, Hisert Katherine B

Abstract excerpt

Highly effective cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulator therapy (HEMT) corrects the underlying molecular defect causing CF disease. HEMT decreases symptom burden and improves clinical metrics and quality of life for most people with CF (PwCF) and eligible cftr mutations. Improvements in measures of pulmonary health suggest that restoration of function of defective CFTR anion...

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Identifiers

PMID: 36344072
DOI: 10.1016/j.ccm.2022.06.007
PMCID: PMC10224747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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