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Article

Estimation of Antibody-Verified Eplet Mismatch Load, 2-Field HLA Resolution vs Imputation in a Large Cohort of European Donors.

Transplantation proceedings - 1 Nov 2022

Renuncio-García Mónica, González-López Elena, Carreras Enric, Villa Juliana, Romón-Alonso Iñigo, Roa-Bautista Adriel, Gutiérrez-Larrañaga María, Comins-Boo Alejandra, Irure-Ventura Juan, López-Hoyos Marcos, San Segundo David

Abstract excerpt

BACKGROUND: The assessment of class II eplet mismatch load is useful to determine the risk of chronic rejection in solid organ transplantation. However, high-resolution (2-field) HLA typing is mandatory to accurately define eplet mismatches. The imputation of the most frequent allele has been used in retrospective studies. Here, we sought to investigate the concordant of antibody-verified (AbV) eplet load in...

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PMID: 36333253
DOI: 10.1016/j.transproceed.2022.09.011

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