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Article

Computational study of the potential impact of AURKC missense SNPs on AURKC-INCENP interaction and their correlation to macrozoospermia.

Journal of biomolecular structure & dynamics - 1 Nov 2023

Redouane Salaheddine, Charoute Hicham, Harmak Houda, Malki Abderrahim, Barakat Abdelhamid, Rouba Hassan

Abstract excerpt

Aurora Kinase C (AURKC) is considered an important element in Chromosome Passenger Complex (CPC), its interaction with Inner Centromere Protein (INCENP) plays a critical role in the establishment and the recruitment of a stable CPC during spermatogenesis. Genetic variations of AURKC gene are susceptible to impact AURKC-INCENP interaction, which may affect CPC stability and predispose male subjects to...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36326488
DOI: 10.1080/07391102.2022.2142846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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