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Whole-exome sequencing identified a novel mutation of AURKC in a Chinese family with macrozoospermia

29 Dec 2018

Abstract excerpt

PURPOSE: Macrozoospermia is a rare sperm morphologic abnormality associated with male infertility and is characterized by a high percentage of spermatozoa with large irregular heads. The aim of this study was to identify the genetic cause of an infertile male with macrozoospermia from a consanguineous family. METHODS: Whole-exome sequencing (WES) was performed using peripheral blood genomic DNA from the patient...

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PMID: 30594972
DOI: 10.1007/s10815-018-1374-3

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