Article
Adult mixed phenotype acute leukemia (MPAL): B/myeloid MPALisoMPO is distinct from other MPAL subtypes.
International journal of laboratory hematology - 1 Apr 2023
Weinberg Olga K, Dennis Jake, Zia Hamid, Chen Pu, Chu Andrew, Koduru Prasad, Luu Hung S, Fuda Franklin, Chen Weina
Abstract excerpt
INTRODUCTION: Myeloperoxidase (MPO) is considered a specific marker of myeloid/non-monocytic lineage in the diagnosis of mixed phenotype acute leukemia (MPAL). However, the clinical significance of isolated dim MPO expression in otherwise typical B lymphoblastic leukemia (B-ALL; referred to as B/myeloid MPALisoMPO ) in adult patients is unknown. METHODS: We compared flow cytometric immunophenotype and...
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