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Loss of heterozygosity detected at three short tandem repeat locus commonly used for human DNA identification in a case of paternity testing.

Legal medicine (Tokyo, Japan) - 1 Jan 2017

Zhou Shiyuan, Wang Haili, Wang Qing K, Wang Pengyun, Wang Fengyu, Xu Chengqi

Abstract excerpt

Short tandem repeat (STR) is widely used for DNA profiling in forensic sciences for its stable inheritance. Genomic variations in STR loci may affect the results of the genotyping. In this study, using STR profiling and genome-wide chromosomal microarray assay, we detected the incidence of uniparental disomy or copy-neutral loss of heterozygosity (LOH) in a case of a parental testing, which altered the genotype...

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PMID: 28081793
DOI: 10.1016/j.legalmed.2016.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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