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Article

Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data.

BMC cancer - 31 Oct 2022

Sorokin Maxim, Zolotovskaia Marianna, Nikitin Daniil, Suntsova Maria, Poddubskaya Elena, Glusker Alexander, Garazha Andrew, Moisseev Alexey, Li Xinmin, Sekacheva Marina, Naskhletashvili David, Seryakov Alexander, Wang Ye, Buzdin Anton

Abstract excerpt

BACKGROUND: Overall survival of advanced colorectal cancer (CRC) patients remains poor, and gene expression analysis could potentially complement detection of clinically relevant mutations to personalize CRC treatments. METHODS: We performed RNA sequencing of formalin-fixed, paraffin-embedded (FFPE) cancer tissue samples of 23 CRC patients and interpreted the data obtained using bioinformatic method Oncobox for...

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Identifiers

PMID: 36316649
DOI: 10.1186/s12885-022-10177-3
PMCID: PMC9623986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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