Article
A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation.
Oncotarget - 6 Oct 2015
Artemov Artem, Aliper Alexander, Korzinkin Michael, Lezhnina Ksenia, Jellen Leslie, Zhukov Nikolay, Roumiantsev Sergey, Gaifullin Nurshat, Zhavoronkov Alex, Borisov Nicolas, Buzdin Anton
Abstract excerpt
A new generation of anticancer therapeutics called target drugs has quickly developed in the 21st century. These drugs are tailored to inhibit cancer cell growth, proliferation, and viability by specific interactions with one or a few target proteins. However, despite formally known molecular tar...
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