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Article

Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer.

BMC cancer - 24 Jun 2020

Altunel Erdem, Roghani Roham S, Chen Kai-Yuan, Kim So Young, McCall Shannon, Ware Kathryn E, Shen Xiling, Somarelli Jason A, Hsu David S

Abstract excerpt

BACKGROUND: Metastatic colorectal cancer (CRC) continues to be a major health problem, and current treatments are primarily for disease control and palliation of symptoms. In this study, we developed a precision medicine strategy to discover novel therapeutics for patients with CRC. METHODS: Six matched low-passage cell lines and patient-derived xenografts (PDX) were established from CRC patients undergoing...

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Identifiers

PMID: 32580713
DOI: 10.1186/s12885-020-07090-y
PMCID: PMC7313200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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