Article
Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population.
Human immunology - 1 Jan 2012
Yang Bin, Chen Jie, Li Yi, Zhang Junlong, Li Dongdong, Huang Zhuochun, Cai Bei, Li Lixin, Shi Yunying, Ying Binwu, Wang Lanlan
Abstract excerpt
The aim of this study was to detect the association between 2 single nucleotide polymorphisms (SNPs), rs2910164 G>C and rs3746444 T>C, in pre-miRNA (hsa-mir-146a and hsa-mir-499) and the chronic inflammation in the Chinese Han population with rheumatoid arthritis (RA). Two hundred sixty-two Han Chinese patients with RA were recruited in this study. The SNPs were genotyped by polymerase chain reaction restriction...
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