Article
Heparanase Upregulation Contributes to Porcine Reproductive and Respiratory Syndrome Virus Release
11 May 2017
Abstract excerpt
ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause substantial economic losses to the pig industry worldwide. Heparan sulfate (HS) is used by PRRSV for initial attachment to target cells. However, the role of HS in the late phase of PRRSV infection and the mechanism of virus release from host cells remain largely unknown. In this study, we showed that PRRSV infection caused a...
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