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Article

STAT6 expression in glioblastoma promotes invasive growth

20 May 2011

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is a highly aggressive malignant primary brain tumor, characterized by rapid growth, diffuse infiltration of cells into both adjacent and remote brain regions, and a generalized resistance to currently available treatment modalities. Recent reports in the literature suggest that Signal Transducers and Activators of Transcription (STATs) play important roles in the regulation of GBM...

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PMID: 21595984
DOI: 10.1186/1471-2407-11-184

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