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The morphology, functionality, and longevity of a novel all human hepatic cell-based tri-culture system

23 Oct 2022

Abstract excerpt

There remains a significant need for a convenient, phenotypically stable long-term culture platform for primary human hepatocytes (PHHs) for use in pharmacological and toxicological applications. Conventional in vitro models are often inconvenient, burdensome to use, and unable to support a multitude of donor lots or maintain PHH structural and functional properties over extended time. To address these...

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PMID: 36288780
DOI: 10.1016/j.tiv.2022.105504

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