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Article

A case of molecularly confirmed BAP1 inactivated melanocytic tumor with retention of immunohistochemical expression: A confounding factor.

Journal of cutaneous pathology - 1 May 2020

Linos Konstantinos, Atkinson Aaron E, Yan Shaofeng, Tsongalis Gregory J, Lefferts Joel A

Abstract excerpt

BRCA1-associated Protein 1 (BAP1)-inactivated melanocytic nevi/tumors (BIMT) have distinct morphologic features. A typical case exhibits a biphasic population of cytologically bland conventional melanocytes and a second proliferation of larger epithelioid melanocytes with abundant eosinophilic cytoplasm. The vast majority of cases harbor BRAF V600E in both components with bi-allelic inactivation of BAP1 in the...

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Source

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Identifiers

PMID: 31891422
DOI: 10.1111/cup.13642
PMCID: PMC10860368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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