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Article

EZH2-mediated H3K27me3 is a predictive biomarker and therapeutic target in uveal melanoma

6 Oct 2022

Abstract excerpt

Although gene mutations and aberrant chromosomes are associated with the pathogenesis and prognosis of uveal melanoma (UM), potential therapeutic targets still need to be explored. We aim to determine the predictive value and potential therapeutic target of EZH2 in uveal melanoma. Eighty-five uveal melanoma samples were recruited in our study, including 19 metastatic and 66 nonmetastatic samples. qRT-PCR,...

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PMID: 36276954
DOI: 10.3389/fgene.2022.1013475

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