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Local Complement Inhibition for Geographic Atrophy in Age-Related Macular Degeneration: Prospects, Challenges, and Unanswered Questions

17 Sept 2021

Abstract excerpt

Geographic atrophy (GA) in age-related macular degeneration (AMD) represents a common, blinding condition that typically is bilateral and relentlessly progressive.1,2 It affects more than 5 million people, with a global prevalence of 0.44%.2 If the fovea is involved, visual acuity typically is very poor. It represents a substantial public health problem because no drugs are approved to slow GA enlargement or to...

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PMID: 36275191
DOI: 10.1016/j.xops.2021.100057

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