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Article

Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: the COMPLETE study.

Ophthalmology - 1 Mar 2014

Yehoshua Zohar, de Amorim Garcia Filho Carlos Alexandre, Nunes Renata Portella, Gregori Giovanni, Penha Fernando M, Moshfeghi Andrew A, Zhang Kang, Sadda Srinivas, Feuer William, Rosenfeld Philip J

Abstract excerpt

PURPOSE: To evaluate the effect of eculizumab, a systemic inhibitor of complement component (C5), on the growth of geographic atrophy (GA) in patients with age-related macular degeneration (AMD). DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Patients with GA measuring from 1.25 to 18 mm(2) based on spectral-domain optical coherence tomography imaging. METHODS: Patients were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24289920
DOI: 10.1016/j.ophtha.2013.09.044
PMCID: PMC4015213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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