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Article

Association of mTORC1‑dependent circulating protein levels with cataract formation: a mendelian randomization study.

BMC genomics - 21 Oct 2022

Cai Yingjun, Liu Kangcheng, Wu Pengfei, Yuan Ruolan, He Fei, Zou Jing

Abstract excerpt

BACKGROUND: The mechanistic target of rapamycin (mTOR) signal pathway plays a critical regulating role in the occurrence and development of cataract. However, the role of mTORC1 downstream proteins, including ribosomal protein S6K (RP-S6K), eukaryotic initiation factor 4E-binding protein (EIF4EBP), eukaryotic initiation factor 4G (EIF-4G), eukaryotic initiation factor 4E (EIF-4E), and eukaryotic initiation factor...

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Identifiers

PMID: 36271348
DOI: 10.1186/s12864-022-08925-7
PMCID: PMC9587558

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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