Evaluation of trail receptor 1 (DR4) polymorphisms C626G and A683C as risk factors of hepatocellular carcinoma.

doi:10.1002/jmv.24964

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Evaluation of trail receptor 1 (DR4) polymorphisms C626G and A683C as risk factors of hepatocellular carcinoma.

Journal of medical virology - 1 Mar 2018

Alsalawy Naglaa F, Darwish Rania K, Kamal Manal M, ElTaweel Ahmed E, Shousha Hend I, Elbaz Tamer M

Abstract excerpt

Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) plays an important role in many cancers including hepatocellular carcinoma (HCC). The aim of this study is to investigate the association of the DR4 polymorphisms C626G (Thr209Arg, rs20575) and A683C (Glu228Ala, rs20576) with the occurrence of HCC in Egyptian patients chronically infected with HCV. The study included 80 patients with HCV-related HCC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Egypt

Share to Epidemiological Monitoring

Share to Fibrosis

Share to Hepatitis C

Share to Liver Neoplasms

Share to Real-Time Polymerase Chain Reaction

Share to Receptors, TNF-Related Apoptosis-Inducing Ligand

Source

Open in PubMed

Identifiers

PMID: 28975649
DOI: 10.1002/jmv.24964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of trail receptor 1 (DR4) polymorphisms C626G and A683C as risk factors of hepatocellular carcinoma.PMID 28975649Read ↗

TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients.Semantic proximity Read ↗

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients.Semantic proximity Read ↗

Association of Polymorphisms in TRAIL and Chronic Hepatitis B in Chinese Han Populations from Shandong Province.Semantic proximity Read ↗

Digging more in the genetic risk prediction of hepatitis C virus epidemic in Egypt: Apoptosis genes polymorphisms in the susceptibility of hepatitis C virus and association with viral load.Semantic proximity Read ↗

Association of DR4 (TRAIL-R1) polymorphisms with cancer risk in Caucasians: an updated meta-analysis.Semantic proximity Read ↗

Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population.Semantic proximity Read ↗

Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population.Semantic proximity Read ↗

Impact of Toll-like Receptors 2(TLR2) and TLR 4 Gene Variations on HCV Susceptibility, Response to Treatment and Development of Hepatocellular Carcinoma in Cirrhotic HCV PatientsSemantic proximity Read ↗

A Meta-Analysis of the Influence of Tumor Necrosis Factor-α-308 Gene Polymorphism on Liver Cirrhosis.Semantic proximity Read ↗

TRAIL-R1 polymorphisms and cancer susceptibility: an evidence-based meta-analysis.Semantic proximity Read ↗

Role of interferon gamma and tumor necrosis factor-related apoptosis-inducing ligand receptor 1 single nucleotide polymorphism in natural clearance and treatment response of HCV infection.Semantic proximity Read ↗

Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.