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Development and characterization of patient-derived salivary gland cancer organoid cultures

17 Oct 2022

Abstract excerpt

OBJECTIVE: Three-dimensional organoid cell cultures have been established for a variety of human cancers. For most rare cancers, including salivary gland cancer (SGC), these models are lacking, despite the great unmet need to study cancer biology in these diseases. Therefore, we aimed to develop patient-derived organoid (PDO) models for different subtypes of SGC. METHODS: cells) were phenotypically characterized...

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PMID: 36265373
DOI: 10.1016/j.oraloncology.2022.106186

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