Article
Vitamin B-6 and riboflavin, their metabolic interaction, and relationship with MTHFR genotype in adults aged 18-102 years.
The American journal of clinical nutrition - 19 Dec 2022
Jarrett Harry, McNulty Helene, Hughes Catherine F, Pentieva Kristina, Strain J J, McCann Adrian, McAnena Liadhan, Cunningham Conal, Molloy Anne M, Flynn Albert, Hopkins Sinead M, Horigan Geraldine, O'Connor Ciara, Walton Janette, McNulty Breige A, Gibney Michael J, Lamers Yvonne, Ward Mary
Abstract excerpt
BACKGROUND: The generation of the active form of vitamin B-6, pyridoxal 5'-phosphate (PLP), in tissues is dependent upon riboflavin as flavin mononucleotide, but whether this interaction is important for maintaining vitamin B-6 status is unclear. OBJECTIVE: To investigate vitamin B-6 and riboflavin status, their metabolic interaction, and relationship with methylenetetrahydrofolate reductase (MTHFR) genotype in...
Topics
- Adult
- Aged
- Humans
- Flavin Mononucleotide
- Genotype
- Methylenetetrahydrofolate Reductase (NADPH2)
- Pyridoxal Phosphate
- Riboflavin
- Vitamin B 12