Article
Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma.
Molecular genetics & genomic medicine - 1 Dec 2022
Eltayeb Majdolin Mohammed, Ali Mohamed M, Omar Saeed M, Mohamed Nouh Saad, Adam Ishag, Hamdan Hamdan Z
Abstract excerpt
BACKGROUND: The polymorphisms of the cyclin-dependent kinase inhibitor (CDKN1A) gene and matrix metalloproteinase-9 (MMP9) gene may increase one's susceptibility to malignancies. In this study, the association of the single nucleotide polymorphisms (SNPs) CDKN1A rs1059234 c.70C>T at the 3' untranslated region and MMP9 rs17576 (c.836A>G, p.Gln279Arg) with esophageal squamous cell carcinoma (ESCC) in Sudanese...
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