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Article

Tau interactome and RNA binding proteins in neurodegenerative diseases

17 Oct 2022

Abstract excerpt

Pathological tau aggregation is a primary neuropathological feature of many neurodegenerative diseases. Intriguingly, despite the common presence of tau aggregates in these diseases the affected brain regions, clinical symptoms, and morphology, conformation, and isoform ratio present in tau aggregates varies widely. The tau-mediated disease mechanisms that drive neurodegenerative disease are still unknown. Tau...

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PMID: 36253823
DOI: 10.1186/s13024-022-00572-6

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