Article
hnRNP A1 , hnRNP A2B1 , and hnRNP K are dysregulated in tauopathies, but do not colocalize with tau pathology
1 Oct 2024
Abstract excerpt
Tau interacts with multiple heterogeneous nuclear ribonucleoproteins (hnRNPs)-a family of RNA binding proteins that regulate multiple known cellular functions, including mRNA splicing, mRNA transport, and translation regulation. We have previously demonstrated particularly significant interactions between phosphorylated tau and three hnRNPs (hnRNP A1, hnRNP A2B1, and hnRNP K). Although multiple hnRNPs have been...
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