Article
miR-516a-3P, a potential circulating biomarker in hepatocellular carcinoma, correlated with rs738409 polymorphism in PNPLA3.
Personalized medicine - 1 Nov 2022
Youssef Samar Samir, Youness Rana Ahmed, Abbas Eman Abd El-Razek, Osman Noha Mohamed, ELFiky Asmaa, El-Kassas Mohamed
Abstract excerpt
Aim: The aim was to investigate the expression profile of miR-516a-3P and its correlation with the PNPLA3 rs738409 polymorphism in Egyptian hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) patients. Materials & methods: miR-516a-3P was quantified and rs738409 was genotyped by quantitative reverse transcription PCR. Results: miR-516a-3P was significantly upregulated in HCC patients compared with HCV...
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