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Mechanistic target of rapamycin signaling in human nervous system development and disease

26 Sept 2022

Abstract excerpt

Mechanistic target of rapamycin (mTOR) is a highly conserved serine/threonine kinase that regulates fundamental cellular processes including growth control, autophagy and metabolism. mTOR has key functions in nervous system development and mis-regulation of mTOR signaling causes aberrant neurodevelopment and neurological diseases, collectively called mTORopathies. In this mini review we discuss recent studies...

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PMID: 36226315
DOI: 10.3389/fnmol.2022.1005631

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