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Article

Mammalian target of rapamycin: master regulator of cell growth in the nervous system.

Histology and histopathology - 1 Aug 2007

Sandsmark D K, Pelletier C, Weber J D, Gutmann D H

Abstract excerpt

The mammalian target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase that regulates a number of diverse biologic processes important for cell growth and proliferation, including ribosomal biogenesis and protein translation. In this regard, hyperactivation of the mTOR signaling pathway has been demonstrated in numerous human cancers, including a number of inherited cancer syndromes in...

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Identifiers

PMID: 17503347
DOI: 10.14670/HH-22.895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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