Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome.

International journal of molecular sciences - 26 Nov 2022

Jiménez-Jiménez Félix Javier, Gómez-Tabales Javier, Alonso-Navarro Hortensia, Rodríguez Christopher, Turpín-Fenoll Laura, Millán-Pascual Jorge, Álvarez Ignacio, Pastor Pau, Calleja Marisol, García-Ruiz Rafael, Navarro-Muñoz Santiago, Recio-Bermejo Marta, Plaza-Nieto José Francisco, García-Albea Esteban, García-Martín Elena, Agúndez José A G

Abstract excerpt

According to several studies, inflammatory factors could be related to the pathogenesis of idiopathic restless legs syndrome (RLS). In addition, RLS and Parkinson's disease (PD) have shown a possible relationship, and recent studies have shown an association between CD4 rs1922452 and CD4 rs951818 single nucleotide variants (SNVs) and the risk for PD. For these reasons, we investigated the possible association...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to CD4 Antigens
Share to Genotype
Share to Parkinson Disease
Share to Polymorphism, Single Nucleotide
Share to Restless Legs Syndrome
Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 36499121
DOI: 10.3390/ijms232314795
PMCID: PMC9739762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome.PMID 36499121Read ↗

Association Between Common Variants in the LAG3/CD4 Genes and Risk for Essential Tremor.Semantic proximity Read ↗

Association between LAG3/CD4 gene variants and risk of Parkinson's disease.Semantic proximity Read ↗

Association between LAG3/CD4 Genes Variants and Risk for Multiple Sclerosis.Semantic proximity Read ↗

Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine.Semantic proximity Read ↗

Lymphocyte-Activation Gene 3 (LAG3) Protein as a Possible Therapeutic Target for Parkinson’s Disease: Molecular Mechanisms Connecting Neuroinflammation to α-Synuclein Spreading PathologySemantic proximity Read ↗

Association of LAG3 genetic variation with an increased risk of PD in Chinese female population.Semantic proximity Read ↗

Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progressionSemantic proximity Read ↗

Association analysis of the LAG3 and CD4 genes in multiple sclerosis in two independent populations.Semantic proximity Read ↗

TOX3 Variants Are Involved in Restless Legs Syndrome and Parkinson's Disease with Opposite Effects.Semantic proximity Read ↗

TOX3 gene variant could be associated with painful restless legs.Semantic proximity Read ↗

Restless legs syndrome in Czech patients with multiple sclerosis: an epidemiological and genetic study.Semantic proximity Read ↗

Association of BTBD9 and MAP2K5/SKOR1 With Restless Legs Syndrome in Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.