Article
MIF is a common genetic determinant of COVID-19 symptomatic infection and severity.
QJM : monthly journal of the Association of Physicians - 27 Mar 2023
Shin J J, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz W L, Unlu S, Kuster J, Young G, Liu J, Ko A I, Baeza Garcia A, Sauler M, Wisnewski A V, Young L, Orduña A, Wang A, Ocskay K, Garcia-Blesa A, Hegyi P, Armstrong M E, Mitchell P D, Bernardo D, Garami A, Kang I, Bucala R
Abstract excerpt
BACKGROUND: Genetic predisposition to coronavirus disease 2019 (COVID-19) may contribute to its morbidity and mortality. Because cytokines play an important role in multiple phases of infection, we examined whether commonly occurring, functional polymorphisms in macrophage migration inhibitory factor (MIF) are associated with COVID-19 infection or disease severity. AIM: To determine associations of common...
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