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Article

Long-term epigenetic and metabolomic changes in the mouse ventricular myocardium after exertional heat stroke

10 Oct 2022

Abstract excerpt

Evidence from human epidemiological studies suggests that exertional heat stroke (EHS) results in an elevated risk of long-term cardiovascular and systemic disease. Previous results using a preclinical mouse model of EHS demonstrated severe metabolic imbalances in ventricular myocardium developing at 9–14 days of recovery. Whether this resolves over time is unknown. We hypothesized that the long-term effects of...

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PMID: 36215393
DOI: 10.1152/physiolgenomics.00147.2021

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