Article
Heat acclimation memory: do the kinetics of the deacclimated transcriptome predispose to rapid reacclimation and cytoprotection?
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Dec 2014
Tetievsky Anna, Assayag Miri, Ben-Hamo Rotem, Efroni Sol, Cohen Gal, Abbas Atallah, Horowitz Michal
Abstract excerpt
Faster reinduction of heat acclimation (AC) after its decline indicates "AC memory." Our previous results revealed involvement of epigenetic mechanisms of transcriptional regulation. We hypothesized that the decline of AC (DeAC) is a period of "dormant memory" during which many processes are alerted to enable rapid reacclimation (ReAC). Using a genomewide approach we studied the AC, DeAC, and ReAC transcriptomes,...
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