Article
Housing Mice in Thermoneutrality Causes Tissue-specific Changes in Number, Identity, and Phase of Circadian-expressed mRNA Transcripts
2026-05-08
Abstract excerpt
Most laboratory mice are housed at room temperature (20-25°C), which exposes them to chronic mild cold stress because it is below their thermoneutral temperature (30°C). We hypothesized that mild cold stress suppresses circadian gene expression in peripheral tissues. We performed RNA sequencing on hearts, livers, and diaphragms collected every 4 hours over 48 hours in constant darkness from male mice to identify t...
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Identifiers and source
- Literature Corpus work
- b2eae6f7-368e-5b13-ba6e-3af7f84c5c03
- DOI
- 10.64898/2026.05.05.722706