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Article

Wnt Signaling in the Phenotype and Function of Tumor-Associated Macrophages.

Cancer research - 4 Jan 2023

Tigue Megan L, Loberg Matthew A, Goettel Jeremy A, Weiss William A, Lee Ethan, Weiss Vivian L

Abstract excerpt

Tumor-associated macrophages (TAM) play an important role in supporting tumor growth and suppressing antitumor immune responses, and TAM infiltration has been associated with poor patient prognosis in various cancers. TAMs can be classified as pro-inflammatory, M1-like, or anti-inflammatory, M2-like. While multiple factors within the tumor microenvironment affect the recruitment, polarization, and functions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36214645
DOI: 10.1158/0008-5472.CAN-22-1403
PMCID: PMC9812914

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