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Article

Phenotypic characterization of Ghanaian P. falciparum clinical isolates reveals a homogenous parasite population.

Frontiers in immunology - 1 Jan 2022

Thiam Laty G, Nyarko Prince B, Ansah Felix, Niang Makhtar, Awandare Gordon A, Aniweh Yaw

Abstract excerpt

Background: Erythrocyte invasion by P. falciparum involves functionally overlapping interactions between the parasite's ligands and the erythrocyte surface receptors. While some P. falciparum isolates necessarily engage the sialic acid (SA) moieties of the erythrocytes during the invasion, others use ligands whose binding is independent of SA for successful invasion. Deciphering the major pathway used by P....

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Identifiers

PMID: 36211335
DOI: 10.3389/fimmu.2022.1009252
PMCID: PMC9537689

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