Article
Functional diversification between two related <i>Plasmodium falciparum</i> merozoite invasion ligands is determined by changes in the cytoplasmic domain
18 Jan 2010
Abstract excerpt
The pathogenesis of Plasmodium falciparum depends on efficient invasion into host erythrocytes. Parasite ligands encoded by multi-gene families interact with erythrocyte receptors. P. falciparum reticulocyte binding protein homologues (PfRhs) are expressed at the apical surface of invasive merozoites and have divergent ectodomains that are postulated to bind different erythrocyte receptors. Variant expression of...
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