Article
Invasion profiles of Brazilian field isolates of Plasmodium falciparum: phenotypic and genotypic analyses.
Infection and immunity - 1 Oct 2004
Lobo Cheryl-Ann, de Frazao Karla, Rodriguez Marilis, Reid Marion, Zalis Mariano, Lustigman Sara
Abstract excerpt
The invasion of red blood cells (RBCs) by Plasmodium falciparum is dependent on multiple molecular interactions between erythrocyte receptors and parasite ligands. Invasion studies using culture-adapted parasite strains have indicated significant receptor heterogeneity. It is not known whether this heterogeneity reflects the parasite invasion arsenal in the field. We have studied the invasion phenotypes of 14...
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