Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single and combined effect of bisphenol A with high sucrose diet on the diabetic and renal tubular dysfunction phenotypes in Drosophila melanogaster.

Environmental toxicology and pharmacology - 1 Nov 2022

Rani Lavi, Saini Sanjay, Thakur Ravindra Singh, Patel Devendra Kumar, Chowdhuri Debapratim Kar, Gautam Naveen Kumar

Abstract excerpt

In the present study, effect of exposure of bisphenol A (BPA) and combined exposure of BPA + HSD has been investigated on the glucose homeostasis and associated renal complications in Drosophila. Exposure of 1.0 mM BPA alone induced type 2 diabetes like condition (T2D) in adult male D. melanogaster via oxidative stress. Elevated TGF-β signaling was evident by increased expression of baboon (babo) in BPA exposed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzhydryl Compounds
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Kidney Diseases

Share to Phenotype

Share to Sucrose

Source

Identifiers

PMID: 36210596
DOI: 10.1016/j.etap.2022.103977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single and combined effect of bisphenol A with high sucrose diet on the diabetic and renal tubular dysfunction phenotypes in Drosophila melanogaster.PMID 36210596Read ↗

Multi-omics Analysis Uncovers Lifespan Effects of Polyethylene and Polystyrene Microplastics Coexposure in Drosophila melanogasterSemantic proximity Read ↗

Drosophila melanogaster diabetes models and its usage in the research of anti-diabetes management with traditional Chinese medicinesSemantic proximity Read ↗

High Glucose-Induced ROS-Accumulation in Zebrafish Larvae Leads to Mitochondria- Mediated ApoptosisSemantic proximity Read ↗

Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish.Semantic proximity Read ↗

Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform.Semantic proximity Read ↗

Diet-Induced Podocyte Dysfunction in Drosophila and MammalsSemantic proximity Read ↗

Non-Genetic-Induced Zebrafish Model for Type 2 Diabetes with Emphasis on Tools in Model ValidationSemantic proximity Read ↗

SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In VivoSemantic proximity Read ↗

Modeling Chronic Arsenic Toxicity in Drosophila melanogaster: Insights into Oxidative Stress, Neurotoxicity, and CarcinogenesisSemantic proximity Read ↗

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.Semantic proximity Read ↗

Type 2 diabetes amplifies environmental Pb toxicity and intergenerational riskSemantic proximity Read ↗

Long-term bisphenol A exposure accelerates insulitis development in diabetes-prone NOD mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.