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Article

A novel approach to assessing bisphenol-A hazards using an in vitro model system

9 Aug 2016

Abstract excerpt

BACKGROUND: Although the toxicological impacts of the xenoestrogen bisphenol-A (BPA) have been studied extensively, but the mechanism of action is poorly understood. Eventually, no standard method exists for evaluating the possible health hazards of BPA exposure. Considering mice spermatozoa as a potential in vitro model, we investigated the effects of BPA exposure (0.0001, 0.01, 1, and 100 μM for 6 h) on...

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PMID: 27507061
DOI: 10.1186/s12864-016-2979-5

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