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Article

Methylation status of <i>VTRNA2-1</i> / <i>nc886</i> is stable across populations, monozygotic twin pairs and in majority of tissues

1 Sept 2022

Abstract excerpt

Aims & methods: The aim of this study was to characterize the methylation level of a polymorphically imprinted gene, VTRNA2-1/nc886, in human populations and somatic tissues.48 datasets, consisting of more than 30 tissues and >30,000 individuals, were used. Results: nc886 methylation status is associated with twin status and ethnic background, but the variation between populations is limited. Monozygotic twin...

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PMID: 36200237
DOI: 10.2217/epi-2022-0228

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