Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes.

Translational psychiatry - 5 Oct 2022

Dannemann Michael, Milaneschi Yuri, Yermakovich Danat, Stiglbauer Victoria, Kariis Hanna Maria, Krebs Kristi, Friese Manuel A, Otte Christian, Lehto Kelli, Penninx Brenda W J H, Kelso Janet, Gold Stefan M

Abstract excerpt

Despite advances in identifying the genetic basis of psychiatric and neurological disorders, fundamental questions about their evolutionary origins remain elusive. Here, introgressed variants from archaic humans such as Neandertals can serve as an intriguing research paradigm. We compared the number of associations for Neandertal variants to the number of associations of frequency-matched non-archaic variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Digestive system and related health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Neurodegenerative Diseases

Share to Genetic Variation

Share to Genome

Share to Haplotypes

Share to Neanderthals

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 36198681
DOI: 10.1038/s41398-022-02196-2
PMCID: PMC9534885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes.PMID 36198681Read ↗

Neandertal introgression dissects the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypesSemantic proximity Read ↗

The phenotypic legacy of admixture between modern humans and Neandertals.Semantic proximity Read ↗

Effects of introgressed Neanderthal alleles on present-day brain morphologySemantic proximity Read ↗

Functional archaic DNA regulates molecular variation and is associated with disease risk across global populationsSemantic proximity Read ↗

The Contribution of Neanderthals to Phenotypic Variation in Modern Humans.Semantic proximity Read ↗

The impact of evolutionary processes in shaping the genetics of complex traits in East Asia and Europe: a specific contribution from Denisovan and Neanderthal introgressionSemantic proximity Read ↗

The Population-Specific Impact of Neandertal Introgression on Human Disease.Semantic proximity Read ↗

Rapid expansion of synaptic complexity as a key contributor to cognitive growth in early humansSemantic proximity Read ↗

Quantifying the contribution of Neanderthal introgression to the heritability of complex traits.Semantic proximity Read ↗

Evaluating the effects of archaic protein-altering variants in living human adultsSemantic proximity Read ↗

Patterns of coding variation in the complete exomes of three Neandertals.Semantic proximity Read ↗

Genomic analysis of the natural history of attention-deficit/hyperactivity disorder using Neanderthal and ancient Homo sapiens samples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.