Article
Germline predisposition to hematopoietic malignancies.
Human molecular genetics - 1 Oct 2021
Feurstein Simone, Drazer Michael, Godley Lucy A
Abstract excerpt
Once thought to be exceedingly rare, the advent of next-generation sequencing has revealed a plethora of germline predisposition disorders that confer risk for hematopoietic malignancies (HMs). These syndromes are now recognized to be much more common than previously thought. The recognition of a germline susceptibility risk allele in an individual impacts the clinical management and health surveillance...
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