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Article

Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying heterozygous FLNC mutations.

Stem cell research - 1 Oct 2022

Kojic Ana, Kim Hobin, Guevara Julio V, Ravada Sai, Sallam Karim, Wu Joseph C

Abstract excerpt

Dilated cardiomyopathy (DCM) is a heterogeneous cardiac disorder characterized by left ventricular dilatation and dysfunction. Mutations in dozens of cardiac genes have been connected to the development of DCM including the filamin C gene (FLNC). We generated two induced pluripotent stem cell (iPSCs) lines from DCM patients carrying single missense heterozygote FLNC mutations (c.6689G > A and c.3745G > A). Both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36194907
DOI: 10.1016/j.scr.2022.102928
PMCID: PMC10871033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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