Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of a human induced pluripotent stem cell line derived from a patient with dilated cardiomyopathy carrying LMNA nonsense mutation.

Stem cell research - 1 Jul 2022

Shimoda Yuzuno, Murakoshi Nobuyuki, Mori Haruka, Xu DongZhu, Tajiri Kazuko, Hemmi Yasuko, Sato Iori, Noguchi Michiya, Nakamura Yukio, Hayashi Yohei, Ieda Masaki

Abstract excerpt

Dilated cardiomyopathy (DCM) is a refractory heart disease characterized by dilation of the left ventricle and systolic dysfunction. LMNA, the gene encoding lamin A/C (a nuclear envelope protein), is the second leading causative gene associated with familial DCM. LMNA-related DCM is likely to develop severe heart failure, various types of arrhythmias, and poor prognosis. We established a human induced pluripotent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Nonsense

Share to Induced Pluripotent Stem Cells

Share to Lamin Type A

Share to Mutation

Source

Identifiers

PMID: 35500377
DOI: 10.1016/j.scr.2022.102793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of a human induced pluripotent stem cell line derived from a patient with dilated cardiomyopathy carrying LMNA nonsense mutation.PMID 35500377Read ↗

Investigating LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Semantic proximity Read ↗

Modeling of LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Generation of human induced pluripotent stem cell line EURACi015-A from a patient affected by dilated cardiomyopathy carrying the Lamin A/C p.Glu161Lys mutation.Semantic proximity Read ↗

Establishment of an iPSC line (JSPHi001-A) from a patient with familial dilated cardiomyopathy and atrial fibrillation caused by LMNA missense mutation (c.1003C > T).Semantic proximity Read ↗

Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients.Semantic proximity Read ↗

Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying heterozygous FLNC mutations.Semantic proximity Read ↗

Modeling Treatment Response for Lamin A/C Related Dilated Cardiomyopathy in Human Induced Pluripotent Stem Cells.Semantic proximity Read ↗

Generation of an iPSC cell line (USFi003-A) from a patient with dilated cardiomyopathy carrying a heterozygous mutation in LMNA (p.R541C).Semantic proximity Read ↗

Induced pluripotent stem cells technology for investigating familial dilated cardiomyopathy due to lamin A/C mutationsSemantic proximity Read ↗

Generation of a human induced pluripotent stem cell line from a pediatric heart failure patient with de novo DNM1L mutation.Semantic proximity Read ↗

Generation of a heterozygous FLNC mutation-carrying human iPSC line, USFi002-A, for modeling dilated cardiomyopathy.Semantic proximity Read ↗

Establishment of a novel human iPSC line (YCMi003-A) from a patient with dilated cardiomyopathy carrying genetic variant LMNA p.Asp364His.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.