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Article

Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients.

Stem cell research - 1 Aug 2022

Caudal Arianne, Mondejar-Parreño Gema, Vera Carlos D, Williams Damon R, Shenoy Sushma P, Liang David, Wu Joseph C

Abstract excerpt

Familial dilated cardiomyopathy (DCM) is among the most prevalent forms of inherited heart disease. Here, two human-induced pluripotent stem cell (iPSC) lines were generated from peripheral blood mononuclear cells (PBMCs) from DCM patients carrying different mutations in the phospholamban encoding-gene (PLN). Both iPSC lines exhibited normal morphology, karyotype, pluripotency marker expression, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35853412
DOI: 10.1016/j.scr.2022.102855
PMCID: PMC9681708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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